Epic has blamed piracy for its decision to switch development resource away from PC and onto console.
The studio's first Gears Of War game reached both PC and Xbox 360 back in 2007, but the sequel never came to the format.
The third game in the series - due for release in April next year - will also be an Xbox 360 exclusive.
"Piracy's already had its impact [on the PC market]," Epic boss Mike Capps told this month's Edge.
"If you walked into this place six years ago, Epic was a PC company and always had been. We did one PS2 launch title, which was a port of Unreal Tournament, and everything else was PC. And now, if you read our forums, people are saying: 'Why do you hate the PC? You're a console-only company.' And guess what? It's because the money's on console.
"We still do PC, we love the PC, but we already saw the impact of piracy: it killed a lot of great independent developers and completely changed our business model."
However, Capps added that things may be looking up for the PC market, as consumers play more in bite-sized chunks than marathon sessions.
"There's certainly a light for PC gaming...," he added. "Most publishers I'm speaking to right now think their money's going to be shifting back to PC and away from traditional consoles, just because folks are in that mode of wanting to spend a little bit of time every now and then, and paying money to save time because there's so much media competing for it.
"... So maybe Facebook will save PC gaming - but it's not going to look like Gears Of War."
Read the full interview with Capps in Edge 215, which is in stores now. Buy your copy of Edge online and have it delivered to your door.