Dead Space 2 debuts atop the UKIE/GfK-ChartTrack All Formats chart for the week ended January 29.
Visceral's sequel knocks LittleBigPlanet 2 down one place to No.2, while FIFA 11 is up one spot to No.3.
Assassin's Creed: Brotherhood and Call of Duty: Black Ops take the next two positions, ahead of Just Dance 2, Need For Speed: Hot Pursuit, Wii Fit Plus, Art Academy and the original Just Dance.
Top 10 (week ended January 29)
01. Dead Space 2 (EA)
02. LittleBigPlanet 2 (Sony)
03. FIFA 11 (EA)
04. Assassin's Creed: Brotherhood (Ubisoft)
05. Call of Duty: Black Ops (Activision)
06. Just Dance 2 (Ubisoft)
07. Need For Speed: Hot Pursuit (EA)
08. Wii Fit Plus (Nintendo)
09. Art Academy (Nintendo)
10. Just Dance (Ubisoft)