Metal Gear Solid 4 saw an aged Snake come wearily to the end of his career as a human weapon, while Metal Gear Solid: Rising looks to take the franchise in a different direction with the young Raiden.
But what about all the sneaking, choking and tranquillising? What about doing a super-small worm along the floor in order to move past enemy guards without being spotted?
The classic stealth aspect of Metal Gear Solid is what made the franchise what it is today and, while we're looking forward to some acrobatic slicing and dicing, we don't want to lose that.
That's why we want to see a Metal Gear Solid 5 that continues with the main principles of the series. But considering the conclusion of Snake's latest adventure, how should it be done?
Here are some of the stylistic and practical things we want to see, tell us what you think in the comments at the end.
Metal Gear Solid: Peace Walker was a massively impressive title for the PSP and a great, true, addition to the Metal Gear franchise.
The strange thing was though that, for all its great little gameplay elements, the cutscenes were way up on our list of reasons to love Peace Walker.
Because of the handheld's lack of power compared to its slick box of a bigger brother, Kojima replaced the typically rich, cinematic Metal Gear cut-scenes with 2D, mostly static comic-book strip style cartoons.
But they were brilliant. Beautifully stylised and dynamically put together, they felt as special and artistic as some of the most well-made sections of the main series, it was just that they offered something completely different.
We're not saying for one minute that we want to get rid of proper 3D FMVs - good grief, that wouldn't do at all - but making good use of the two would be very well received.
Although Metal Gear Solid 4 seemed pretty conclusive as far as Snake's story is concerned we really can't see anyone else taking the protagonist role.
As cool as Raiden was in the Guns of the Patriots, Kojima Productions clearly has other ideas for the acrobatic, sword-swinger in his own series starting with Rising.
So the blonde one's a bit pre-occupied meaning, if we want a familiar face with a proven record, we're probably best sticking with Snake and we think the only way that's going to happen is with a prequel.
Some might throw the classic "Or is it?" response at such a notion, but we think that even if the MGS team could come up with a plausible way to carry on Snake's story, despite his old age and more peaceful outlook, they probably shouldn't.
We're pretty sure Metal Gear Solid 4 brought our man's story to an end and before it did that we were playing with a super soldier who suffered from back-pain if he crouched for too long. There's clearly no mileage left in the old war-dog. There is, however, plenty in Snake's past that could be embellished on further.
The third Metal Gear Solid, Snake Eater, saw a different type of gameplay brought to the series, one where players had to utilise more survival tactics than just shadowy sleuthing.
With the depths of the jungle as its setting, Snake Eater offered a number of new game mechanics that gave a boost to the series and made it a favourite among many of the fans.
While we'd probably have to head back to the jungle in Metal Gear Solid 5 if we wanted to add past-times like hunting for food, climbing trees and patching wounds, we're quite happy to revisit that period of Snake's career.