Take-Two shares fell on Tuesday following disappointing review scores for Duke Nukem Forever and lower than expected first month sales of LA Noire.
The publisher's shares closed down by more than four percent on Tuesday, the day the game hit US retail, MarketWatch reports.
After 14 or so years in development, the game has only managed a 55 Metacritic rating across the Xbox 360 and PS3 versions.
Meanwhile, LA Noire may have been the bestselling game in the States in May, moving a total of 899,000 copies, but that still fell short of some million-plus analyst forecasts.
Take-Two stock is still up more than 20 percent for the year, but has lost more than 15 percent since mid-May, when impressive LA Noire review scores saw it trading at the highest since September 2008.
Cowen & Company analyst Doug Creutz said in a research note that he now believes the possibility of the company achieving its full-year earnings target "has been significantly reduced".