A man who is probably a lot smarter than us has fiddled with Kinect and the PC version of The Elder Scrolls V: Skyrim to get them to play nice with each other.
When we say play nice, we mean it. From the looks of the video showing the mod in action, Skyrim works pretty well with Kinect.
As well as allowing players to swing and thrust their arms to attack with swords and spells, they can also use the voice controls to activate Shouts and navigate menus. This is implemented through a Bluetooth headset.
Have a look in the video below.