The creative director at NetherRealm Studios, Ed Boon, has suggested that a sequel to Mortal Kombat vs. DC Universe is unlikely because of plans to develop both series separately.
Boon told CVG that both the DC Comics and Mortal Kombat games work best when nurtured individually for their own dedicated audiences.
"We don't have any current plans to mash the two franchises together again," he said.
"Never say never, of course, but we loved how our last Mortal Kombat game was strictly Mortal Kombat. And when you think about it, the last Mortal Kombat game we did, it really had the essence of the series more so than any other game in years.
"With Mortal Kombat vs. DC Universe, there's two pretty different audiences; one which wants to see violence and blood, and there's another that wants to see grand superhero moments. We were kind of balancing on a fence trying to accommodate both audiences with Mortal Kombat vs. DC."
NetherRealm, owned by media conglomerate Warner Bros., is currently finishing up production on Injustice: Gods Among Us, which is due for release in the first half of 2013.
Boon said the game "is something that just embraces what's best about superheroes".
He added: "It's a battle of the gods, over-the-top experience. There's no trade-off trying to balance it with Mortal Kombat.
"Funnily enough, we were playing Mortal Kombat vs. DC and we were surprised at how tame it was compared to Injustice."