Activision will pull all Guitar Hero, DJ Hero and Band Hero DLC from sale on April 1.
The company said on its Facebook page that Guitar Hero servers will stay online and any previously purchased DLC will be unaffected by today's news.
As a thank you to the Hero community, select songs and tracks will be discounted by as much 50 per cent on Xbox 360, PS3 and Wii from now until the end of March.
Additionally, the Guitar Hero mobile game has been discounted until the end of the month, after which it too will be pulled from sale.
Activision announced plans to disband its Guitar Hero business unit in February 2011, noting that it "simply cannot make these games profitable given the current market", although the possibility of reinventing the series was mooted by the company on numerous occasions subsequently.
In March 2011, retail monitor the NPD Group named 2007 release Guitar Hero 3 the biggest revenue generator in US videogame history. At the time, the game had raked in $831 million in retail sales, including bundles with guitar controllers, but not including money made from DLC.