Mario Kart 8 sales hit 1.2 million units over the game's first weekend of availability, according to internal Nintendo figures.
Having launched in Japan on Thursday May 29 and in Europe and the Americas the following day, the racer has become the fastest-selling Wii U game to date.
Nintendo is hoping the release of Mario Kart 8 can kickstart a turnaround for the console globally following disappointing Wii U sales in the year ended March 2014.
Chart-Track said on Monday that the UK release of the game helped boost weekly Wii U sales by 666 per cent, while weekly Japanese console sales are generally confirmed on Wednesdays by retail monitor Media Create.
"The early response to Mario Kart 8 demonstrates that the best days for Wii U are still ahead," said Nintendo of America president Reggie Fils-Aime. "This year's E3 is just days away, and it will be all about the future games for Nintendo platforms. This milestone is a great place to start."
As of March 31 2014, the previous games in the series have sold a combined total of over 100 million units worldwide:
- Super Mario Kart (SNES) - 8.76 million
- Mario Kart 64 (N64) - 9.87 million
- Mario Kart Advance (GBA) - 5.91 million
- Mario Kart: Double Dash (GameCube) - 6.88 million
- Mario Kart DS (DS) - 23.56 million
- Mario Kart Wii (Wii) - 35.53 million
- Mario Kart 7 (3DS) - 9.62 million
- Total: 100.13 million
"This is Nintendo serving up unprecedented helpings of joy as only it can," we said in our Mario Kart 8 review. "Each and every track is a delight to experience," it reads, and "the master of karting is a real looker to boot."
See what other critics thought of the racer in our Mario Kart 8 review round-up.