While the publisher isn't planning to end support for the system, it's being highly selective about what it releases in light of underwhelming Wii U sales since the console's November 2012 launch.
"It's very simple," Yves Guillemot told Game Informer. "What we see is that Nintendo customers don't buy Assassin's Creed. Last year, we sold in very small numbers."
Software sales on Nintendo home consoles reportedly accounted for just three per cent of Ubisoft's total for the business year ended in March 2014, down one percentage point from the previous 12 months.
Guillemot said of Nintendo home console owners: "What we see is that they are very interested in Just Dance, very interested by other kinds of games. So what we are trying to do is to focus more on the types of games they are interested in."
The executive added that Ubisoft hasn't abandoned plans to release a previously confirmed version of Watch Dogs on Wii U. "[Watch Dogs] is coming to Wii U. It will be the only mature game we publish on it."
In June, Guillemot said Ubisoft was holding back a finished Wii U game until the console's user base grew sufficiently to warrant marketing investment in the title.